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Different views of the dynamic landscape covered by the 5'-hairpin of the 7SK small nuclear RNA

The 7SK small nuclear RNA (7SKsnRNA) plays a key role in the regulation of RNA polymerase II by sequestrating and inhibiting the positive transcription elongation factor b (P-TEFb) in the 7SK ribonucleoprotein complex (7SKsnRNP), a process mediated by interaction with the protein HEXIM. P-TEFb is al...

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Detalles Bibliográficos
Autores principales: Brillet, Karl, Martinez-Zapien, Denise, Bec, Guillaume, Ennifar, Eric, Dock-Bregeon, Anne-Catherine, Lebars, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430674/
https://www.ncbi.nlm.nih.gov/pubmed/32430362
http://dx.doi.org/10.1261/rna.074955.120