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RNA secondary structures in Dscam1 mutually exclusive splicing: unique evolutionary signature from the midge

The Drosophila melanogaster gene Dscam1 potentially generates 38,016 distinct isoforms via mutually exclusive splicing, which are required for both nervous and immune functions. However, the mechanism underlying splicing regulation remains obscure. Here we show apparent evolutionary signatures chara...

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Detalles Bibliográficos
Autores principales: Hong, Weiling, Shi, Yang, Xu, Bingbing, Jin, Yongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430681/
https://www.ncbi.nlm.nih.gov/pubmed/32471818
http://dx.doi.org/10.1261/rna.075259.120