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Cerebrospinal fluid endo-lysosomal proteins as potential biomarkers for Huntington’s disease

Molecular markers derived from cerebrospinal fluid (CSF) represent an accessible means of exploring the pathobiology of Huntington’s disease (HD) in vivo. The endo-lysosomal/autophagy system is dysfunctional in HD, potentially contributing to disease pathogenesis and representing a potential target...

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Detalles Bibliográficos
Autores principales: Lowe, Alexander J., Sjödin, Simon, Rodrigues, Filipe B., Byrne, Lauren M., Blennow, Kaj, Tortelli, Rosanna, Zetterberg, Henrik, Wild, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430717/
https://www.ncbi.nlm.nih.gov/pubmed/32804976
http://dx.doi.org/10.1371/journal.pone.0233820