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SOX10-regulated promoter use defines isoform-specific gene expression in Schwann cells

BACKGROUND: Multicellular organisms adopt various strategies to tailor gene expression to cellular contexts including the employment of multiple promoters (and the associated transcription start sites (TSSs)) at a single locus that encodes distinct gene isoforms. Schwann cells—the myelinating cells...

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Detalles Bibliográficos
Autores principales: Fogarty, Elizabeth A., Kitzman, Jacob O., Antonellis, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430845/
https://www.ncbi.nlm.nih.gov/pubmed/32770939
http://dx.doi.org/10.1186/s12864-020-06963-7