Model-Informed Development of Sotalol Loading and Dose Escalation Employing an Intravenous Infusion

BACKGROUND: Sotalol is often employed to prevent recurrence of symptomatic atrial flutter/atrial fibrillation. Because sotalol can prolong the QT interval excessively causing ventricular arrhythmias, a 3-day in-hospital loading or dose escalation period is mandated with oral administration in the pr...

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Detalles Bibliográficos
Autores principales: Somberg, John C., Vinks, Alexander A., Dong, Min, Molnar, Janos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430892/
https://www.ncbi.nlm.nih.gov/pubmed/32849964
http://dx.doi.org/10.14740/cr1143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430892/
https://www.ncbi.nlm.nih.gov/pubmed/32849964
http://dx.doi.org/10.14740/cr1143

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