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A structural framework for unidirectional transport by a bacterial ABC exporter

The ATP-binding cassette (ABC) transporter of mitochondria (Atm1) mediates iron homeostasis in eukaryotes, while the prokaryotic homolog from Novosphingobium aromaticivorans (NaAtm1) can export glutathione derivatives and confer protection against heavy-metal toxicity. To establish the structural fr...

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Detalles Bibliográficos
Autores principales: Fan, Chengcheng, Kaiser, Jens T., Rees, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430982/
https://www.ncbi.nlm.nih.gov/pubmed/32703810
http://dx.doi.org/10.1073/pnas.2006526117