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Ancestral roles of atypical cadherins in planar cell polarity

Fat, Fat-like, and Dachsous family cadherins are giant proteins that regulate planar cell polarity (PCP) and cell adhesion in bilaterians. Their evolutionary origin can be traced back to prebilaterian species, but their ancestral function(s) are unknown. We identified Fat-like and Dachsous cadherins...

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Detalles Bibliográficos
Autores principales: Brooun, Maria, Klimovich, Alexander, Bashkurov, Mikhail, Pearson, Bret J., Steele, Robert E., McNeill, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7430989/
https://www.ncbi.nlm.nih.gov/pubmed/32727892
http://dx.doi.org/10.1073/pnas.1917570117