Harmful DNA:RNA hybrids are formed in cis and in a Rad51-independent manner

DNA:RNA hybrids constitute a well-known source of recombinogenic DNA damage. The current literature is in agreement with DNA:RNA hybrids being produced co-transcriptionally by the invasion of the nascent RNA molecule produced in cis with its DNA template. However, it has also been suggested that rec...

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Detalles Bibliográficos
Autores principales: Lafuente-Barquero, Juan, García-Rubio, Maria Luisa, Martin-Alonso, Marta San, Gómez-González, Belén, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431130/
https://www.ncbi.nlm.nih.gov/pubmed/32749214
http://dx.doi.org/10.7554/eLife.56674

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431130/
https://www.ncbi.nlm.nih.gov/pubmed/32749214
http://dx.doi.org/10.7554/eLife.56674

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