Subcellular hot spots of GPCR signaling promote vascular inflammation

G-coupled protein receptors (GPCRs) comprise the largest class of druggable targets. Signaling by GPCRs is initiated from subcellular hot spots including the plasma membrane, signalosomes, and endosomes to contribute to vascular inflammation. GPCR-G protein signaling at the plasma membrane causes en...

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Detalles Bibliográficos
Autores principales: Birch, Cierra A., Molinar-Inglis, Olivia, Trejo, JoAnn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431397/
https://www.ncbi.nlm.nih.gov/pubmed/32838054
http://dx.doi.org/10.1016/j.coemr.2020.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431397/
https://www.ncbi.nlm.nih.gov/pubmed/32838054
http://dx.doi.org/10.1016/j.coemr.2020.07.011

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