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Systems biology reveals reprogramming of the S-nitroso-proteome in the cortical and striatal regions of mice during aging process

Cell aging depends on the rate of cumulative oxidative and nitrosative damage to DNA and proteins. Accumulated data indicate the involvement of protein S-nitrosylation (SNO), the nitric oxide (NO)-mediated posttranslational modification (PTM) of cysteine thiols, in different brain disorders. However...

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Detalles Bibliográficos
Autores principales: Kartawy, Maryam, Khaliulin, Igor, Amal, Haitham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431412/
https://www.ncbi.nlm.nih.gov/pubmed/32807865
http://dx.doi.org/10.1038/s41598-020-70383-6