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Decreased expression of the thyroid hormone-inactivating enzyme type 3 deiodinase is associated with lower survival rates in breast cancer

Thyroid hormones (THs) are critical regulators of cellular processes, while changes in their levels impact all the hallmarks of cancer. Disturbed expression of type 3 deiodinase (DIO3), the main TH-inactivating enzyme, occurs in several human neoplasms and has been associated with adverse outcomes....

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Detalles Bibliográficos
Autores principales: Goemann, Iuri Martin, Marczyk, Vicente Rodrigues, Recamonde-Mendoza, Mariana, Wajner, Simone Magagnin, Graudenz, Marcia Silveira, Maia, Ana Luiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431418/
https://www.ncbi.nlm.nih.gov/pubmed/32807826
http://dx.doi.org/10.1038/s41598-020-70892-4