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Decreased expression of the thyroid hormone-inactivating enzyme type 3 deiodinase is associated with lower survival rates in breast cancer
Thyroid hormones (THs) are critical regulators of cellular processes, while changes in their levels impact all the hallmarks of cancer. Disturbed expression of type 3 deiodinase (DIO3), the main TH-inactivating enzyme, occurs in several human neoplasms and has been associated with adverse outcomes....
Autores principales: | Goemann, Iuri Martin, Marczyk, Vicente Rodrigues, Recamonde-Mendoza, Mariana, Wajner, Simone Magagnin, Graudenz, Marcia Silveira, Maia, Ana Luiza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431418/ https://www.ncbi.nlm.nih.gov/pubmed/32807826 http://dx.doi.org/10.1038/s41598-020-70892-4 |
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