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Nucleotide-Binding Oligomerization Domain-Like Receptor 3 Deficiency Attenuated Isoproterenol-Induced Cardiac Fibrosis via Reactive Oxygen Species/High Mobility Group Box 1 Protein Axis

Nucleotide-binding oligomerization domain-like receptor 3 (NLRP3) is involved in fibrosis of multiple organs, such as kidney, liver, lung, and the like. However, the role of NLRP3 in cardiac fibrosis is still controversial and remains unclear. The study aims to investigate the role of NLRP3 on cardi...

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Detalles Bibliográficos
Autores principales: Liu, Chen, Hu, Tongtong, Cai, Zhulan, Xie, Qingwen, Yuan, Yuan, Li, Ning, Xie, Saiyang, Yao, Qi, Zhao, Jinhua, Wu, Qing Qing, Tang, Qizhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431462/
https://www.ncbi.nlm.nih.gov/pubmed/32850832
http://dx.doi.org/10.3389/fcell.2020.00713