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Clustering by phenotype and genome-wide association study in autism

Autism spectrum disorder (ASD) has phenotypically and genetically heterogeneous characteristics. A simulation study demonstrated that attempts to categorize patients with a complex disease into more homogeneous subgroups could have more power to elucidate hidden heritability. We conducted cluster an...

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Detalles Bibliográficos
Autores principales: Narita, Akira, Nagai, Masato, Mizuno, Satoshi, Ogishima, Soichi, Tamiya, Gen, Ueki, Masao, Sakurai, Rieko, Makino, Satoshi, Obara, Taku, Ishikuro, Mami, Yamanaka, Chizuru, Matsubara, Hiroko, Kuniyoshi, Yasutaka, Murakami, Keiko, Ueno, Fumihiko, Noda, Aoi, Kobayashi, Tomoko, Kobayashi, Mika, Usuzaki, Takuma, Ohseto, Hisashi, Hozawa, Atsushi, Kikuya, Masahiro, Metoki, Hirohito, Kure, Shigeo, Kuriyama, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431539/
https://www.ncbi.nlm.nih.gov/pubmed/32807774
http://dx.doi.org/10.1038/s41398-020-00951-x