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Early overnutrition sensitizes the growth hormone axis to the impact of diet-induced obesity via sex-divergent mechanisms

In addition to its essential role in the physiological control of longitudinal growth, growth-hormone (GH) is endowed with relevant metabolic functions, including anabolic actions in muscle, lipolysis in adipose-tissue and glycemic modulation. Adult obesity is known to negatively impact GH-axis, the...

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Detalles Bibliográficos
Autores principales: Sanchez-Garrido, M. A., Ruiz-Pino, F., Pozo-Salas, A. I., Castellano, J. M., Vazquez, M. J., Luque, R. M., Tena-Sempere, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431568/
https://www.ncbi.nlm.nih.gov/pubmed/32807904
http://dx.doi.org/10.1038/s41598-020-70898-y