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Human NMD ensues independently of stable ribosome stalling
Nonsense-mediated mRNA decay (NMD) is a translation-dependent RNA degradation pathway that is important for the elimination of faulty, and the regulation of normal, mRNAs. The molecular details of the early steps in NMD are not fully understood but previous work suggests that NMD activation occurs a...
Autores principales: | Karousis, Evangelos D., Gurzeler, Lukas-Adrian, Annibaldis, Giuditta, Dreos, René, Mühlemann, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431590/ https://www.ncbi.nlm.nih.gov/pubmed/32807779 http://dx.doi.org/10.1038/s41467-020-17974-z |
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