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Administration of Amyloid Precursor Protein Gene Deleted Mouse ESC-Derived Thymic Epithelial Progenitors Attenuates Alzheimer's Pathology

Alzheimer's disease (AD) is a devastating neurodegenerative disorder and the most common cause of dementia in older adults. Although amyloid-beta (Aβ) plaque deposition and chronic neuroinflammation in the central nervous system (CNS) contribute to AD pathology, neither Aβ plaque removal nor an...

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Detalles Bibliográficos
Autores principales: Zhao, Jin, Su, Min, Lin, Yujun, Liu, Haiyan, He, Zhixu, Lai, Laijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431620/
https://www.ncbi.nlm.nih.gov/pubmed/32849642
http://dx.doi.org/10.3389/fimmu.2020.01781