Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts

Replicative senescence is a hallmark of aging, which also contributes to individual aging. Mouse embryonic fibroblasts (MEFs) provide a convenient replicative senescence model. However, the heterogeneity of single MEFs during cellular senescence has remained unclear. Here, we conducted single-cell R...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Wang, Xuefei, Wei, Gang, Huang, Yin, Shi, Yufang, Li, Dan, Qiu, Shengnu, Zhou, Bin, Cao, Junhong, Chen, Meng, Qin, Pengfei, Jin, Wenfei, Ni, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431633/
https://www.ncbi.nlm.nih.gov/pubmed/32849838
http://dx.doi.org/10.3389/fgene.2020.00867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431633/
https://www.ncbi.nlm.nih.gov/pubmed/32849838
http://dx.doi.org/10.3389/fgene.2020.00867

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