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Ocular Gene Therapy with Adeno-associated Virus Vectors: Current Outlook for Patients and Researchers

In this “Perspective”, we discuss ocular gene therapy – the patient's perspective, the various strategies of gene replacement and gene editing, the place of adeno-associated virus vectors, routes of delivery to the eye and the remaining question - “why does immunity continue to limit efficacy?”...

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Detalles Bibliográficos
Autores principales: Casey, Geoffrey A., Papp, Kimberly M., MacDonald, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PUBLISHED BY KNOWLEDGE E 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431728/
https://www.ncbi.nlm.nih.gov/pubmed/32864069
http://dx.doi.org/10.18502/jovr.v15i3.7457