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Roles of N6-Methyladenosine (m(6)A) in Stem Cell Fate Decisions and Early Embryonic Development in Mammals

N6-methyladenosine (m(6)A) is one of the most abundant internal mRNA modifications, and it affects multiple biological processes related to eukaryotic mRNA. The majority of m(6)A sites are located in stop codons and 3′UTR regions of mRNAs. m(6)A regulates RNA metabolism, including alternative splici...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Zhai, Yanhui, Zhang, Sheng, Dai, Xiangpeng, Li, Ziyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431753/
https://www.ncbi.nlm.nih.gov/pubmed/32850871
http://dx.doi.org/10.3389/fcell.2020.00782