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Syntheses of spliceostatins and thailanstatins: a review
The spliceostatins/thailanstatins are a family of linear peptides/polyketides that inhibit pre-mRNA splicing, and as such act as potent cytotoxic compounds. These compounds generally contain 9 stereocenters spread over a common (2Z,4S)-4-acetoxy-2-butenamide fragment, an (all-cis)-2,3,5,6-tetrasubst...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Beilstein-Institut
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431757/ https://www.ncbi.nlm.nih.gov/pubmed/32831956 http://dx.doi.org/10.3762/bjoc.16.166 |