Synthesis of monophosphorylated lipid A precursors using 2-naphthylmethyl ether as a protecting group

Lipid A, the hydrophobic domain of lipopolysaccharide (LPS), is a strong immunostimulator and therefore a valuable target for the development of novel immunomodulators. Various lipid A derivatives have been chemically synthesized in order to reduce toxicity while retaining the immunostimulatory acti...

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Detalles Bibliográficos
Autores principales: Xue, Jundi, Han, Ziyi, Li, Gen, Emmanuel, Khalisha A, McManus, Cynthia L, Sui, Qiang, Ge, Dongmian, Gao, Qi, Cai, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2020
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431767/
https://www.ncbi.nlm.nih.gov/pubmed/32831952
http://dx.doi.org/10.3762/bjoc.16.162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431767/
https://www.ncbi.nlm.nih.gov/pubmed/32831952
http://dx.doi.org/10.3762/bjoc.16.162

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