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Synthesis of monophosphorylated lipid A precursors using 2-naphthylmethyl ether as a protecting group

Lipid A, the hydrophobic domain of lipopolysaccharide (LPS), is a strong immunostimulator and therefore a valuable target for the development of novel immunomodulators. Various lipid A derivatives have been chemically synthesized in order to reduce toxicity while retaining the immunostimulatory acti...

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Detalles Bibliográficos
Autores principales:	Xue, Jundi, Han, Ziyi, Li, Gen, Emmanuel, Khalisha A, McManus, Cynthia L, Sui, Qiang, Ge, Dongmian, Gao, Qi, Cai, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2020
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431767/ https://www.ncbi.nlm.nih.gov/pubmed/32831952 http://dx.doi.org/10.3762/bjoc.16.162

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