The SIRT6 activator MDL‐800 improves genomic stability and pluripotency of old murine‐derived iPS cells

Cellular reprogramming is an emerging strategy for delaying the aging processes. However, a number of challenges, including the impaired genome integrity and decreased pluripotency of induced pluripotent stem cells (iPSCs) derived from old donors, may hinder their potential clinical applications. Th...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Chen, Jiayu, Sun, Xiaoxiang, Yu, Jiayu, Qian, Zhen, Wu, Li, Xu, Xiaojun, Wan, Xiaoping, Jiang, Ying, Zhang, Jian, Gao, Shaorong, Mao, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431819/
https://www.ncbi.nlm.nih.gov/pubmed/33089974
http://dx.doi.org/10.1111/acel.13185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431819/
https://www.ncbi.nlm.nih.gov/pubmed/33089974
http://dx.doi.org/10.1111/acel.13185

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