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Liver osteopontin is required to prevent the progression of age‐related nonalcoholic fatty liver disease

Osteopontin (OPN), a senescence‐associated secretory phenotype factor, is increased in patients with nonalcoholic fatty liver disease (NAFLD). Cellular senescence has been associated with age‐dependent hepatosteatosis. Thus, we investigated the role of OPN in the age‐related hepatosteatosis. For thi...

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Detalles Bibliográficos
Autores principales: Gómez‐Santos, Beatriz, Saenz de Urturi, Diego, Nuñez‐García, Maitane, Gonzalez‐Romero, Francisco, Buque, Xabier, Aurrekoetxea, Igor, Gutiérrez de Juan, Virginia, Gonzalez‐Rellan, Maria J., García‐Monzón, Carmelo, González‐Rodríguez, Águeda, Mosteiro, Lorena, Errazti, Gaizka, Mifsut, Patricia, Gaztambide, Sonia, Castaño, Luis, Martin, Cesar, Nogueiras, Rubén, Martinez‐Chantar, María L., Syn, Wing‐Kin, Aspichueta, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431823/
https://www.ncbi.nlm.nih.gov/pubmed/32638492
http://dx.doi.org/10.1111/acel.13183