The aged hematopoietic system promotes hippocampal‐dependent cognitive decline

The aged systemic milieu promotes cellular and cognitive impairments in the hippocampus. Here, we report that aging of the hematopoietic system directly contributes to the pro‐aging effects of old blood on cognition. Using a heterochronic hematopoietic stem cell (HSC) transplantation model (in which...

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Detalles Bibliográficos
Autores principales: Smith, Lucas K., Verovskaya, Evgenia, Bieri, Gregor, Horowitz, Alana M., von Ungern‐Sternberg, Saskia N. I., Lin, Karin, Seizer, Peter, Passegué, Emmanuelle, Villeda, Saul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Short Take
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431826/
https://www.ncbi.nlm.nih.gov/pubmed/33073926
http://dx.doi.org/10.1111/acel.13192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431826/
https://www.ncbi.nlm.nih.gov/pubmed/33073926
http://dx.doi.org/10.1111/acel.13192

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