Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation in macrophages

Although aggravated liver injury has been reported in aged livers post‐ischemia and reperfusion (IR), the underlying mechanism of innate immune activation of aged macrophages is not well understood. Here, we investigated whether and how Stimulator of interferon genes (STING) signaling regulated macr...

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Detalles Bibliográficos
Autores principales: Zhong, Weizhe, Rao, Zhuqing, Rao, Jianhua, Han, Guoyong, Wang, Ping, Jiang, Tao, Pan, Xiongxiong, Zhou, Shun, Zhou, Haoming, Wang, Xuehao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431827/
https://www.ncbi.nlm.nih.gov/pubmed/32666684
http://dx.doi.org/10.1111/acel.13186

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431827/
https://www.ncbi.nlm.nih.gov/pubmed/32666684
http://dx.doi.org/10.1111/acel.13186

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