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Aging aggravated liver ischemia and reperfusion injury by promoting STING‐mediated NLRP3 activation in macrophages
Although aggravated liver injury has been reported in aged livers post‐ischemia and reperfusion (IR), the underlying mechanism of innate immune activation of aged macrophages is not well understood. Here, we investigated whether and how Stimulator of interferon genes (STING) signaling regulated macr...
Autores principales: | Zhong, Weizhe, Rao, Zhuqing, Rao, Jianhua, Han, Guoyong, Wang, Ping, Jiang, Tao, Pan, Xiongxiong, Zhou, Shun, Zhou, Haoming, Wang, Xuehao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431827/ https://www.ncbi.nlm.nih.gov/pubmed/32666684 http://dx.doi.org/10.1111/acel.13186 |
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