RTN4B‐mediated suppression of Sirtuin 2 activity ameliorates β‐amyloid pathology and cognitive impairment in Alzheimer's disease mouse model

Sirtuin 2 (SIRT2) is an NAD+ dependent deacetylase that is the most abundant sirtuin protein in the brain. Accumulating evidence revealed the role of SIRT2 in a wide range of biological processes and age‐related diseases. However, the pivotal mechanism of SIRT2 played in Alzheimer's disease (AD...

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Detalles Bibliográficos
Autores principales: Wang, Yan, Yang, Jing‐Qi, Hong, Ting-Ting, Sun, Yuan‐Hong, Huang, Hai‐Li, Chen, Feng, Chen, Xiong‐Jin, Chen, Hui‐Yi, Dong, Shan‐Shan, Cui, Li‐Li, Yang, Tie‐Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431833/
https://www.ncbi.nlm.nih.gov/pubmed/32700357
http://dx.doi.org/10.1111/acel.13194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431833/
https://www.ncbi.nlm.nih.gov/pubmed/32700357
http://dx.doi.org/10.1111/acel.13194

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