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Addressing the batch effect issue for LC/MS metabolomics data in data preprocessing

With the growth of metabolomics research, more and more studies are conducted on large numbers of samples. Due to technical limitations of the Liquid Chromatography–Mass Spectrometry (LC/MS) platform, samples often need to be processed in multiple batches. Across different batches, we often observe...

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Detalles Bibliográficos
Autores principales: Liu, Qin, Walker, Douglas, Uppal, Karan, Liu, Zihe, Ma, Chunyu, Tran, ViLinh, Li, Shuzhao, Jones, Dean P., Yu, Tianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431853/
https://www.ncbi.nlm.nih.gov/pubmed/32807888
http://dx.doi.org/10.1038/s41598-020-70850-0