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CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair

Chromatin organization is critical for cell growth, differentiation, and disease development, however, its functions in peripheral myelination and myelin repair remain elusive. In this report, we demonstrate that the CCCTC-binding factor (CTCF), a crucial chromatin organizer, is essential for Schwan...

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Detalles Bibliográficos
Autores principales: Wang, Jincheng, Wang, Jiajia, Yang, Lijun, Zhao, Chuntao, Wu, Laiman Natalie, Xu, Lingli, Zhang, Feng, Weng, Qinjie, Wegner, Michael, Lu, Q. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431862/
https://www.ncbi.nlm.nih.gov/pubmed/32807777
http://dx.doi.org/10.1038/s41467-020-17955-2