Indoleamine 2,3-Dioxygenase 2 Deficiency Exacerbates Imiquimod-Induced Psoriasis-Like Skin Inflammation

Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme known to suppress immune responses, and several reports have showed that it is associated with psoriasis. IDO2 is an isoform of IDO1, recently identified as a catalytic enzyme in the tryptophan-kynurenine pathway, which is expressed in dendritic cell...

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Detalles Bibliográficos
Autores principales: Fujii, Kento, Yamamoto, Yasuko, Mizutani, Yoko, Saito, Kuniaki, Seishima, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432009/
https://www.ncbi.nlm.nih.gov/pubmed/32752186
http://dx.doi.org/10.3390/ijms21155515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432009/
https://www.ncbi.nlm.nih.gov/pubmed/32752186
http://dx.doi.org/10.3390/ijms21155515

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