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Indoleamine 2,3-Dioxygenase 2 Deficiency Exacerbates Imiquimod-Induced Psoriasis-Like Skin Inflammation

Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme known to suppress immune responses, and several reports have showed that it is associated with psoriasis. IDO2 is an isoform of IDO1, recently identified as a catalytic enzyme in the tryptophan-kynurenine pathway, which is expressed in dendritic cell...

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Detalles Bibliográficos
Autores principales:	Fujii, Kento, Yamamoto, Yasuko, Mizutani, Yoko, Saito, Kuniaki, Seishima, Mariko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432009/ https://www.ncbi.nlm.nih.gov/pubmed/32752186 http://dx.doi.org/10.3390/ijms21155515

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