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Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels

Misfolding, aggregation and accumulation of proteins are toxic elements in the progression of a broad range of neurodegenerative diseases. Molecular chaperones enable a cellular defense by reducing or compartmentalizing these insults. Small heat shock proteins (sHsps) engage proteins early in the pr...

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Detalles Bibliográficos
Autores principales: Webster, Jack M., Darling, April L., Sanders, Taylor A., Blazier, Danielle M., Vidal-Aguiar, Yamile, Beaulieu-Abdelahad, David, Plemmons, Drew G., Hill, Shannon E., Uversky, Vladimir N., Bickford, Paula C., Dickey, Chad A., Blair, Laura J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432035/
https://www.ncbi.nlm.nih.gov/pubmed/32751642
http://dx.doi.org/10.3390/ijms21155442