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Hsp22 with an N-Terminal Domain Truncation Mediates a Reduction in Tau Protein Levels
Misfolding, aggregation and accumulation of proteins are toxic elements in the progression of a broad range of neurodegenerative diseases. Molecular chaperones enable a cellular defense by reducing or compartmentalizing these insults. Small heat shock proteins (sHsps) engage proteins early in the pr...
Autores principales: | Webster, Jack M., Darling, April L., Sanders, Taylor A., Blazier, Danielle M., Vidal-Aguiar, Yamile, Beaulieu-Abdelahad, David, Plemmons, Drew G., Hill, Shannon E., Uversky, Vladimir N., Bickford, Paula C., Dickey, Chad A., Blair, Laura J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432035/ https://www.ncbi.nlm.nih.gov/pubmed/32751642 http://dx.doi.org/10.3390/ijms21155442 |
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