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Mitochondrial Respiration Changes in R6/2 Huntington’s Disease Model Mice during Aging in a Brain Region Specific Manner

Mitochondrial dysfunction is crucially involved in aging and neurodegenerative diseases, such as Huntington’s Disease (HD). How mitochondria become compromised in HD is poorly understood but instrumental for the development of treatments to prevent or reverse resulting deficits. In this paper, we in...

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Detalles Bibliográficos
Autores principales: Burtscher, Johannes, Di Pardo, Alba, Maglione, Vittorio, Schwarzer, Christoph, Squitieri, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432063/
https://www.ncbi.nlm.nih.gov/pubmed/32751413
http://dx.doi.org/10.3390/ijms21155412