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The Artemisinin-Derived Autofluorescent Compound BG95 Exerts Strong Anticytomegaloviral Activity Based on a Mitochondrial Targeting Mechanism

Human cytomegalovirus (HCMV) is a major human pathogen associated with severe pathology. Current options of antiviral therapy only partly satisfy the needs of a well-tolerated long-term treatment/prophylaxis free from drug-induced viral resistance. Recently, we reported the strong antiviral properti...

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Detalles Bibliográficos
Autores principales: Wild, Markus, Hahn, Friedrich, Grau, Benedikt, Herrmann, Lars, Niesar, Aischa, Schütz, Martin, Lorion, Melanie M., Ackermann, Lutz, Tsogoeva, Svetlana B., Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432203/
https://www.ncbi.nlm.nih.gov/pubmed/32759737
http://dx.doi.org/10.3390/ijms21155578