Loss of Caveolin-1 Is Associated with a Decrease in Beta Cell Death in Mice on a High Fat Diet

Elevated free fatty acids (FFAs) impair beta cell function and reduce beta cell mass as a consequence of the lipotoxicity that occurs in type 2 diabetes (T2D). We previously reported that the membrane protein caveolin-1 (CAV1) sensitizes to palmitate-induced apoptosis in the beta pancreatic cell lin...

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Detalles Bibliográficos
Autores principales: Lillo Urzúa, Paloma, Núñez Murillo, Olinda, Castro-Sepúlveda, Mauricio, Torres-Quintana, María A., Lladser Caldera, Álvaro, Quest, Andrew F. G., Espinoza Robles, Carolina, Llanos Vidal, Paola, Wehinger, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432291/
https://www.ncbi.nlm.nih.gov/pubmed/32718046
http://dx.doi.org/10.3390/ijms21155225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432291/
https://www.ncbi.nlm.nih.gov/pubmed/32718046
http://dx.doi.org/10.3390/ijms21155225

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