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Melatonin Suppresses Renal Cortical Fibrosis by Inhibiting Cytoskeleton Reorganization and Mitochondrial Dysfunction through Regulation of miR-4516

Renal fibrosis, a major risk factor for kidney failure, can lead to chronic kidney disease (CKD) and is caused by cytoskeleton reorganization and mitochondrial dysfunction. In this study, we investigated the potential of melatonin treatment to reduce renal fibrosis by recovering the cytoskeleton reo...

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Detalles Bibliográficos
Autores principales: Yoon, Yeo Min, Go, Gyeongyun, Yun, Chul Won, Lim, Ji Ho, Lee, Jun Hee, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432329/
https://www.ncbi.nlm.nih.gov/pubmed/32727098
http://dx.doi.org/10.3390/ijms21155323