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The Effects of Antipsychotics on the Synaptic Plasticity Gene Homer1a Depend on a Combination of Their Receptor Profile, Dose, Duration of Treatment, and Brain Regions Targeted

Background: Antipsychotic agents modulate key molecules of the postsynaptic density (PSD), including the Homer1a gene, implicated in dendritic spine architecture. How the antipsychotic receptor profile, dose, and duration of administration may influence synaptic plasticity and the Homer1a pattern of...

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Detalles Bibliográficos
Autores principales: Iasevoli, Felice, Buonaguro, Elisabetta Filomena, Avagliano, Camilla, Barone, Annarita, Eramo, Anna, Vellucci, Licia, de Bartolomeis, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432375/
https://www.ncbi.nlm.nih.gov/pubmed/32756473
http://dx.doi.org/10.3390/ijms21155555