Predicting Carcinogenic Mechanisms of Non-Genotoxic Carcinogens via Combined Analysis of Global DNA Methylation and In Vitro Cell Transformation

An in vitro cell transformation assay (CTA) is useful for the detection of non-genotoxic carcinogens (NGTXCs); however, it does not provide information on their modes of action. In this study, to pursue a mechanism-based approach in the risk assessment of NGTXCs, we aimed to develop an integrated st...

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Detalles Bibliográficos
Autores principales: Hwang, Sung-Hee, Yeom, Hojin, Han, Byeal-I, Ham, Byung-Joo, Lee, Yong-Moon, Han, Mi-Ryung, Lee, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432388/
https://www.ncbi.nlm.nih.gov/pubmed/32751172
http://dx.doi.org/10.3390/ijms21155387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432388/
https://www.ncbi.nlm.nih.gov/pubmed/32751172
http://dx.doi.org/10.3390/ijms21155387

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