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Uveal Melanoma Cells Elicit Retinal Pericyte Phenotypical and Biochemical Changes in an in Vitro Model of Coculture

Vascular pericytes are an important cellular component in the tumor microenvironment, however, their role in supporting cancer invasion is poorly understood. We hypothesized that PDGF-BB could be involved in the transition of human retinal pericytes (HRPC) in cancer-activated fibroblasts (CAF), indu...

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Detalles Bibliográficos
Autores principales: Anfuso, Carmelina Daniela, Longo, Anna, Distefano, Alfio, Amorini, Angela Maria, Salmeri, Mario, Zanghì, Guido, Giallongo, Cesarina, Giurdanella, Giovanni, Lupo, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432414/
https://www.ncbi.nlm.nih.gov/pubmed/32756477
http://dx.doi.org/10.3390/ijms21155557