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The Role of Protein Tyrosine Phosphatases in Inflammasome Activation

Inflammasomes are multi-protein complexes that mediate the activation and secretion of the inflammatory cytokines IL-1β and IL-18. More than half a decade ago, it has been shown that the inflammasome adaptor molecule, ASC requires tyrosine phosphorylation to allow effective inflammasome assembly and...

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Detalles Bibliográficos
Autores principales: Spalinger, Marianne R., Schwarzfischer, Marlene, Scharl, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432435/
https://www.ncbi.nlm.nih.gov/pubmed/32751912
http://dx.doi.org/10.3390/ijms21155481