Functional Alterations in the Olfactory Neuronal Circuit Occur before Hippocampal Plasticity Deficits in the P301S Mouse Model of Tauopathy: Implications for Early Diagnosis and Translational Research in Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by neuronal loss and impaired synaptic transmission, ultimately leading to cognitive deficits. Early in the disease, the olfactory track seems most sensitive to tauopathy, while most plasticity studies focused on the hippocampal circuits. Functional network...

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Detalles Bibliográficos
Autores principales: Ahnaou, Abdallah, Rodriguez-Manrique, Daniela, Biermans, Ria, Embrechts, Sofie, Manyakov, Nikolay V., Drinkenburg, Wilhelmus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432464/
https://www.ncbi.nlm.nih.gov/pubmed/32751531
http://dx.doi.org/10.3390/ijms21155431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432464/
https://www.ncbi.nlm.nih.gov/pubmed/32751531
http://dx.doi.org/10.3390/ijms21155431

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