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Mechanisms of Action for Small Molecules Revealed by Structural Biology in Drug Discovery

Small-molecule drugs are organic compounds affecting molecular pathways by targeting important proteins. These compounds have a low molecular weight, making them penetrate cells easily. Small-molecule drugs can be developed from leads derived from rational drug design or isolated from natural resour...

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Detalles Bibliográficos
Autores principales: Li, Qingxin, Kang, CongBao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432558/
https://www.ncbi.nlm.nih.gov/pubmed/32722222
http://dx.doi.org/10.3390/ijms21155262