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Hallmarks of frailty and osteosarcopenia in prematurely aged PolgA((D257A/D257A)) mice
BACKGROUND: Frailty is a geriatric syndrome characterized by increased susceptibility to adverse health outcomes. One major determinant thereof is the gradual weakening of the musculoskeletal system and the associated osteosarcopenia. To improve our understanding of the underlying pathophysiology an...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432580/ https://www.ncbi.nlm.nih.gov/pubmed/32596975 http://dx.doi.org/10.1002/jcsm.12588 |