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Hallmarks of frailty and osteosarcopenia in prematurely aged PolgA((D257A/D257A)) mice

BACKGROUND: Frailty is a geriatric syndrome characterized by increased susceptibility to adverse health outcomes. One major determinant thereof is the gradual weakening of the musculoskeletal system and the associated osteosarcopenia. To improve our understanding of the underlying pathophysiology an...

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Detalles Bibliográficos
Autores principales: Scheuren, Ariane C., D'Hulst, Gommaar, Kuhn, Gisela A., Masschelein, Evi, Wehrle, Esther, De Bock, Katrien, Müller, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432580/
https://www.ncbi.nlm.nih.gov/pubmed/32596975
http://dx.doi.org/10.1002/jcsm.12588