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A randomized crossover trial of elamipretide in adults with primary mitochondrial myopathy

BACKGROUND: This study aims to evaluate the effect of subcutaneous (SC) elamipretide dosing on exercise performance using the 6 min walk test (6MWT), patient‐reported outcomes measuring fatigue, functional assessments, and safety to guide the development of the Phase 3 trial. METHODS: MMPOWER‐2 was...

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Detalles Bibliográficos
Autores principales: Karaa, Amel, Haas, Richard, Goldstein, Amy, Vockley, Jerry, Cohen, Bruce H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432581/
https://www.ncbi.nlm.nih.gov/pubmed/32096613
http://dx.doi.org/10.1002/jcsm.12559