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Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia

BACKGROUND: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer‐associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy caused by systemic inflammation is a major cl...

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Detalles Bibliográficos
Autores principales: Chiappalupi, Sara, Sorci, Guglielmo, Vukasinovic, Aleksandra, Salvadori, Laura, Sagheddu, Roberta, Coletti, Dario, Renga, Giorgia, Romani, Luigina, Donato, Rosario, Riuzzi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432590/
https://www.ncbi.nlm.nih.gov/pubmed/32159297
http://dx.doi.org/10.1002/jcsm.12561