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Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia
BACKGROUND: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer‐associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy caused by systemic inflammation is a major cl...
Autores principales: | Chiappalupi, Sara, Sorci, Guglielmo, Vukasinovic, Aleksandra, Salvadori, Laura, Sagheddu, Roberta, Coletti, Dario, Renga, Giorgia, Romani, Luigina, Donato, Rosario, Riuzzi, Francesca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432590/ https://www.ncbi.nlm.nih.gov/pubmed/32159297 http://dx.doi.org/10.1002/jcsm.12561 |
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