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Long‐term human IgG treatment improves heart and muscle function in a mouse model of Duchenne muscular dystrophy

BACKGROUND: Duchenne muscular dystrophy (DMD) is a progressive muscle‐wasting disease caused by mutations in the dystrophin gene, which leads to structural instability of the dystrophin–glycoprotein‐complex with subsequent muscle degeneration. In addition, muscle inflammation has been implicated in...

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Detalles Bibliográficos
Autores principales: Zschüntzsch, Jana, Jouvenal, Pia Vanessa, Zhang, Yaxin, Klinker, Florian, Tiburcy, Malte, Liebetanz, David, Malzahn, Dörthe, Brinkmeier, Heinrich, Schmidt, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432639/
https://www.ncbi.nlm.nih.gov/pubmed/32436338
http://dx.doi.org/10.1002/jcsm.12569